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[2014 Spring Life Sciences & IBB Regular Seminar]
▶Subject: Plant Glucose Signaling Networks
▶Speaker: Jen Sheen, Ph.D. (Department of Genetics, Harvard Medical School )
▶Place: Auditorium(1F), Postech Biotech Center
Glucose fuels life from bacteria to plants and humans. Despite the essential and multifaceted regulatory roles of glucose in gene expression, physiology, metabolism, cell proliferation, growth and development, and connections to human diseases, the molecular and cellular mechanisms of glucose signaling remain enigmatic in multicellular plants and animals. Novel concepts and innovative approaches are essential to reveal surprises that keep us excited in pursuing the mystery of sugar regulation in life, which has been taken for granted in our daily life but poorly understood. I will present a simple model of the glucose signaling networks in plants, highlighting three master regulators that are evolutionarily conserved from yeasts to plants and humans. These key sensors that either directly sensing glucose signals in different biological contexts or indirectly sensing glucose-derived energy status to globally regulate transcription and plant growth and development, encompassing meristem activation, cell elongation and differentiation. The glucose signaling networks form the indispensible regulatory framework to support other regulatory systems modulated by hormones, peptides, and environmental cues. Each sensor has multiple subcellular locales and action partners and substrates to regulate different aspects of the nutrient regulatory networks, which is subjected to environmental modulations by light, other nutrients, stresses and microbes. We hope to establish new paradigms in glucose responses and regulation in plants and animals, and build a new conceptual framework to enhance our understanding of the molecular and cellular mechanisms of plant glucose signaling.
▶Inquiry: Prof.Hwang, Il-Doo (279-2291)
* This seminar will be given in English