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DeepTetrad: high-throughput image analysis of meiotic tetrads by deep …

  • 저널명The Plant Journal ;101(2):473-483
    • 담당교수Kyuha Choi
    • 조회125
    • 작성자최고관리자
    • 2020-04-29

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    ■ SUMMARY
    Meiotic crossovers facilitate chromosome segregation and create new combinations of alleles in gametes.
    Crossover frequency varies along chromosomes and crossover interference limits the coincidence of closely
    spaced crossovers. Crossovers can be measured by observing the inheritance of linked transgenes expressing
    different colors of fluorescent protein in Arabidopsis pollen tetrads. Here we establish DeepTetrad, a
    deep learning-based image recognition package for pollen tetrad analysis that enables high-throughput
    measurements of crossover frequency and interference in individual plants. DeepTetrad will accelerate the
    genetic dissection of mechanisms that control meiotic recombination.
     


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