We provide the computing tools and information to solve problems and create hypotheses in all areas of biological sciences.
We focus on the DNA damage and repair that play a critical role in a genomic stability. Therefore, we provide a mechanism for cancer prevention or therapeutic attack.
We focus on the search, design, and optimization of an antibody and a small molecule that increase specific affinity for target protein.
We provide molecular mechanism of membrane proteins that mediated transport of ion and molecules across lipid bilayer or detect molecules outside the cell and activate internal signal transduction pathway.
We investigate the proliferation processes of pathogenic viruses, develop diagnostic and therapeutic tools for them, and study the mechanisms of anti-viral innate and adaptive immunity of host cells.
We investigate the interactions of various microorganisms present in the gut and identify their effects on the host immune system to discover microorganisms capable of treating cancer, autoimmunity and allergic diseases
We investigate the mechanism of anti-cancer immunotherapeutic agents that have recently shown breakthrough cancer treatment outcomes, and conduct basic and clinical studies to discover new targets and apply them to patient treatment.
Based on in-depth study of stem cell biology, the principles of cell fate determination and organismal development will be explored, which lay out a framework for therapeutics development along with the cutting-edge organoid-based disease modeling.
Research on protein and organelle homeostasis advances our knowledge regarding the importance of cellular dynamics in a variety of diseases and thereby provide new drug targeting molecules.
Epigenetics involving remodeling of chromatin and DNA modifications combined with systems biology that integrates multiple disciplines lay the foundations for quantitative analysis of genomic data and systems-level dynamics modeling towards understanding of complexity in living organisms.
To investigate the molecular, cellular mechanisms and neural circuitry of memory involved in fear and addiction by behavioral studies of animal models and electrophysiological techniques in neurons.
To investigate the molecular mechanisms of neurological and psychiatric disorders caused by functional abnormalities in the brain development using stem cell and animal disease models.
To investigate the molecular mechanisms of structural and functional changes in individual synapses which ultimately lead to activity-dependent gene expression and cell-wide adaptation mechanism that permit synaptic and behavioral plasticity to be long-lasting.
we conduct cutting-edge scientific research that leads to breakthroughs in our understanding of growth, development, differentiation and genetic diversity in model and cultivated plant systems. In particular, our researches focus on control of plant vascular development, membrane transporters and genomic recombination to maximize biomass and contribute to food security and conservation.
we aim to understand the mechanism of plant immune system against pathogens based on microbiology, molecular biology, genetics and bioinformatics. We use model, natural and cultivated plants for our researches. We are developing the invaluable biotechnologies that prevent reduction in plant production due to pathogen infections.
we are developing plants as a system for production of green biomaterials in particular recombinant proteins. Using the plant-produced proteins, we aim to develop highly valuable protein-based products such as pharmaceuticals, green biosimilar and green vaccines, and also environmentally sound and highly efficient enzyme-based production processes.