최관용 교수 Profile

  • 경력
  • 논문
  • 연구분야
| Education |
B.S., Seoul National University, Seoul, Korea (1975)
M.S., Korea Advanced Institute of Science and Technology, Korea (1977)
Ph.D., University of California, Davis, CA, USA (1988)

| Career |
1988~1989: Postdoctoral Fellow University of California, Medical School
1989~1990: NRC Research Associate, National Institutes of Health
1990~Present: Assistant, Associate, and Full Professor, POSTECH
1. Cha HJ et al., Structural analysis combined with small-angle X-ray scattering reveals that the retention of heme is critical for maintaining the structure of horseradish peroxidase under denaturing conditions. Amino Acids. 2017
2. Kim ES et al., Identification of caveolin-1 as an invasion-associated gene in liver cancer cells using Dendron-coatedd DNA microarrays Appl Biochem Biotechnol. 2017
3. Hong SM et al. NAMPT suppresses glucose deprivation-induced oxidative stress by increasing NADPH levels in breast cancer. Oncogene. 2016
4. Lee N et al., Interactomic analysis of REST/NRSF and implications of its functional links with the transcription suppressor TRIM28 during neuronal differentiation. Sci Rep. 2016
5. Lee N et al., SIRT6 Depletion Suppresses Tumor Growth by Promoting Cellular Senescence Induced by DNA Damage in HCC. PLoS One. 2016
6. Cha et al., Role of conserved Met112 residue in the catalytic activity and stability of ketosteroid isomerase. Biochim Biophys Acta. 2016
7. Lee N et al., Vaccinia-related kinase 1 promotes hepatocellular carcinoma by controlling the levels of cell cycle regulators associated with G1/S transition. Oncotarget. 2015
8. Lee N et al., Comparative interactomes of SIRT6 and SIRT7: Implication of functional links to aging. Proteomics. 2014
9. Kim ES et al., Kinetic characterization of on-chip DNA ligation on dendron-coated surfaces with nanoscaled lateral spacings. Nanotechnology. 2013
10. Park CW et al., BNIP3 is degraded by ULK1-dependent autophagy via MTORC1 and AMPK. Autophagy. 2013
| Research Areas |
Protein networks in the interactome of cancer, aging and metabolism
Roles and interactions of key effector molecules in autophagy, apoptosis and metastasis in cancer, aging and metabolic diseases
Engineering of recombinant proteins and nano molecules for biomedical application